Raymond Wong

If you noticed baseline drift with your chromatography; common causes are listed below.     Causes Solutions Column temperature fluctuation - Control column temperature. Low quality mobile ...

If you notice loss or changes in sensitivity; common causes are described below.     Causes Solutions Injector issue - Changes in dispensing volume of injector, use a system suitability sampl...

If your chromatography has recently been losing resolution; common causes are described below.     Causes Solutions Changes in peak width - Changes in column performance and sample load / col...

If you notice your retention times are variable and changing; common causes are listed below.     Causes Solutions Flow rate - Check the method uses the correct flow rate. Ensure the flow rat...

If you notice extra peaks in your typical chromatograms; potential causes are listed below.     Causes Solutions Other components in sample - It is normal to see extra peaks if they are prese...

If your chromatographic peaks transition from narrow sharp peaks to broad peaks; common causes are listed below.     Causes Solutions Sample loading - Reduce sample concentration or injection...

If your chromatography begins to demonstrate fronting resulting in poor peak asymmetry; common causes are listed below.     Causes Suggestions Column degradation - Replace the column. Mobil...

If your chromatography has recently started to demonstrate tailing peaks; this could be related to common causes described below.     Causes Solutions Secondary interactions - For bases incre...

If your chromatography has recently demonstrated this phenomena of split peaks some common causes are described below.     Causes Solutions Soiled guard or column inlet - Replace guard or inl...

If your chromatogram no longer has peaks being displayed some common causes could be related below.      Causes Solutions Detector setting issue - Check the detector lamp is turned on.- Check...