
Raymond Wong
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Articles
Recent activity by Raymond Wong-
Improving Peak Shapes Affected by Sample Solvents in UHPLC Systems
This article describes how if peak broadening occurs due to sample solvent effects, the “co-injection” automatic pretreatment function included with Nexera XR systems can be used to improve peak ...
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Sequence Analysis of Antisense Nucleic Acid (oligonucleotide) using MALDI-8030
Mass spectrometry (MS) has now become an established analytical tool for analyzing biopolymers, such as nucleic acids, proteins, and glycans, thanks to the development of various soft ionization me...
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Manifold attachment kit
If you would like to use a 6 port manifold attachment kit in your system. Please use the following part number. 228-72436-41 Manifold Attachment Kit Alternatively use a 2nd flow selecti...
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Strong diluent effects in SFC
Ethyl acetate < Acetone < Chloroform < Methanol STD 6 5 mg/mL (20 uL) comparison Note: Acetone exhibits a UV signal at the T0 as well.
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Purification Tips: Volume Load versus Concentration Load with SFC
Injection volume and sample concentration are studied to select the proper loading amount. There are two methods to increase loading amount: “Concentration Load” (increasing concentration of the sa...
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SFC Separation of racemic Verapamil
+/- Racemic Verapamil is prescribed as treatment for Angina. Although one enantiomer is more potent. System: Nexera UC - SFC System Mobile phase: 20% 15 mM Ammonium acetate in IPA : 80% supercritic...
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Solubility of common buffers in THF
Buffers can cause various problems in the lab. Two common problems include surprising rises in HPLC-MS backpressures when starting the instrument after overnight storage and difficulties with MS se...
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Solubility of common buffers in Acetonitrile
Buffers can cause various problems in the lab. Two common problems include surprising rises in HPLC-MS backpressures when starting the instrument after overnight storage and difficulties with MS se...
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Solubility of common buffers in Methanol
Buffers can cause various problems in the lab. Two common problems include surprising rises in HPLC-MS backpressures when starting the instrument after overnight storage and difficulties with MS se...
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Mobile Phase Monitoring (MPM) Options
For gravimetric monitoring of mobile phase levels in real-time and active warnings. The MPM options can be added to your system. Notes: One Main Unit Controller handles up to 6 bottle holders (e.g....